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// research project · 03

Collective
Cell Migration_

Confocal MicroscopyFRETERK Signaling Live-cell ImagingImageJPythonVertex Modeling
institutionMBI, NUS Singapore
labHirashima Group
periodMay 2023 – Jun 2024
statuspreprint · bioRxiv 2026
Collective Cell Migration

// overview

This project investigated how transient perturbations to actomyosin contractility reprogram MDCK epithelial cells from a junctional-tension-dominated state into a protrusion-driven, fluidized tissue state using FRET-based ERK biosensors and live-cell imaging pipelines.

// links